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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract:

Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimentalWe investigated the potential role of GLP-2 pretreatment on hepatic I/R injury in rats.pretreated I/R (GLP2-IR) group.Each rat in the third group was intraperitoneally administered 5 μg GLP-2 for 5 d before the procedureOur data suggested that GLP-2 pretreatment may have a protective effect on liver I/R injury.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 433-444 doi: 10.1007/s11705-014-1454-6

Abstract: Previous studies have found that three peptide inhibitors (i.e., KLVFF, VVIA, and LPFFD) can inhibitHowever, atomic details of binding modes and binding affinities between these peptide inhibitors andmolecular mechanics Poisson Boltzmann surface area (MM/PBSA) analysis, we examined the effect of three peptideMM/PBSA analysis further revealed that different peptide inhibitors have different modes of interactionprovides structure-based binding information for further modification and optimization of these three peptide

Keywords： Alzheimer’s disease     amyloid β-protein     peptide inhibitors     protein-protein interaction     molecular    

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visible-photocatalytic hydrogen evolution and simultaneous organic pollutant degradation over an urchin-like

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 10, doi: 10.1007/s11783-022-1566-z

Abstract:

● An urchin-like OMS/ZIS composite was fabricated by a facile solvothermal

Keywords： Dual-functional photocatalysts     Oxygen-doped MoS2/ZnIn2S4     H2   

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Orlistat induces ferroptosis-like cell death of lung cancer cells

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 922-932 doi: 10.1007/s11684-020-0804-7

Abstract: single agent, inhibited the proliferation and viabilities of lung cancer cells and induced ferroptosis-likegenome-wide gene expression changes affected by orlistat treatment using RNA-seq and identified FAF2,

Keywords： orlistat     ferroptosis     FAF2     lung cancer    

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: Neuropilin and tolloid-like 2 (NETO2) is closely related to tumorigenesis.However, the functional significance of NETO2 in melanoma progression remains unclear.Herein, we found that NETO2 expression was augmented in melanoma clinical tissues and associated withBy contrast, NETO2 overexpression had the opposite effects.indicating that targeting NETO2 may effectively improve melanoma treatment.

Keywords： melanoma     neuropilin and tolloid-like 2     Ca2+/CaMKII signaling pathway    

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Cystine oligomers successfully attached to peptide cysteine-rich fibrils

Christian Bortolini,Mingdong Dong

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1,   Pages 99-102 doi: 10.1007/s11705-016-1554-6

Abstract: In this work, we exploited amyloid-like fibrils as functional material to attach pristine L-cysteine

Keywords： cysteine     peptide fibrils     gold nanoparticles     amyloids     oligomers     nanomaterials    

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Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease

Min Fei, Li Xiang, Xichen Chai, Jingchun Jin, Tao You, Yiming Zhao, Changgeng Ruan, Yiwen Hao, Li Zhu

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 81-90 doi: 10.1007/s11684-019-0692-x

Abstract: Accumulating evidence suggests that C-type lectin-like receptor-2 (CLEC-2) plays an important role inIn this case-control study, we investigated the association between CLEC-2 and incidence of coronaryPlasma levels of soluble CLEC-2 (sCLEC-2) were measured using the enzyme-linked immunosorbent assay (Restricted cubic splines showed a positive dose-response association between sCLEC2 and CAD incidenceof sCLEC-2 may be evaluated in future prospective studies.

Keywords： soluble C-type lectin-like receptor-2     coronary artery disease     risk factor    

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Graphene-like -BN supported polyhedral NiS/NiS nanocrystals with excellent photocatalytic performance

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 6,   Pages 1537-1549 doi: 10.1007/s11705-021-2094-2

Abstract: In this work, h-BN/NiS2/NiS composites were prepared via a simple solvothermal methodThe 7 wt-% h-BN/NiS2/NiS composites were characterized via a larger specific surfaceexperimental result indicated that the photoreduction efficiency of the 7 wt-% h-BN/NiS2h-BN/NiS2/NiS photocatalyst reachedhole scavengers upon the photoreduction of Cr(VI) was studied, the results indicated that graphene-like

Keywords： graphene-like h-BN     h-BN/NiS2/NiS composites     photocatalysis     Cr(VI) reduction    

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The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 437-442 doi: 10.1007/s11684-009-0074-x

Abstract: Natriuretic peptide precursor A (NPPA) is synthesized, stored, and released by atrial myocytes.

Keywords： natriuretic peptide precursor A     coronary heart disease     gene polymorphism     allelic discrimination     polymorphism    

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Mercury removal from aqueous solution using petal-like MoS2

Ragini Pirarath, Palani Shivashanmugam, Asad Syed, Abdallah M. Elgorban, Sambandam Anandan, Muthupandian Ashokkumar

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 1, doi: 10.1007/s11783-020-1307-0

Abstract: Abstract • Synthesized few-layered MoS2 nanosheets via surfactant-assisted hydrothermal method. • SynthesizedMoS2 nanosheets show petal-like morphology. • Adsorbent showed 93% of mercury removal efficiency. •In this work, we synthesized few-layered MoS2 nanosheets via a surfactant-assisted hydrothermal methodThe synthesized MoS2 nanosheets showed petal-like morphology as confirmed by scanning electron microscope91% and 79% removal efficiency in the respective 2nd and 3rd cycles.

Keywords： Anionic surfactant     2D material     MoS2 nanosheets     Mercury removal     Adsorption capacity    

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Bamboo-like -doped carbon nanotubes encapsulating M(Co, Fe)-Ni alloy for electrochemical production of

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 4,   Pages 498-510 doi: 10.1007/s11705-021-2082-6

Abstract: The electrochemical conversion of CO2-H2O into CO-H2 using renewableLow-cost electrocatalysts to produce tunable syngas with a potential-independent CO/H2 ratioThe MxNi-NCNT samples exhibited bamboo-like nanotubular structures with a large specificMore importantly, stable CO/H2 ratios of 2:1 and 1.5:1, corresponding to the ratio to produce/sub> ratio from electrochemical CO2 reduction.

Keywords： electrochemical reduction of CO2     syngas     N-doped carbon nanotubes     encapsulated alloynanoparticles     CO/H2 ratio    

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Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine

Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 65-71 doi: 10.15302/J-FASE-2016086

Abstract: Previous studies have shown that a pSn V-set Ig-like domain is significant in PRRSV infection.In this study, we successfully cloned, expressed and purified the pSn V-set Ig-like domain in S2 cells

Keywords： PRRSV     porcine sialoadhesin     V-set Ig-like domain     Drosophila S2 cell     crystallization    

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Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 9-19 doi: 10.1007/s11705-013-1306-9

Abstract: innovative silica-based, mucoadhesive oral insulin formulation with encapsulated-insulin/cell penetrating peptideIt was also confirmed that low molecular weight protamine (LMWP) behaves like a CPP peptide, with a celldevelopment of a generic platform for oral delivery of many other bioactive compounds, especially for peptide

Keywords： insulin     cell penetrating peptide     mucoadhesive composites     oral delivery    

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Effects of oxidizing environment on digestate humification and identification of substances governing the dissolved organic matter (DOM) transformation process

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1520-0

Abstract:

• Liquid digestate humification was investigated under different oxidizing environment.

Keywords： Liquid digestate     MnO2     Oxygen     DOM transformation     Humic-like acids    

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Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Engineering doi: 10.1016/j.eng.2023.01.015

Abstract: In particular, a designed antifreeze peptide named AVD exhibits ideal ice recrystallization inhibitionanalysis and molecular dynamics (MD) simulations indicated that the Thr6 and Asn8 residues of the AVD peptideFurthermore, to demonstrate the cryoprotection potential of AVD, the peptide was successfully employedThis work opens up a new avenue for designing antifreeze materials and provides peptide-based functional

Keywords： Antifreeze peptides     Evolution analysis     Ice recrystallization inhibition     Molecular dynamics simulation     Cryopreservation     Synthetic biology    

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Title Author Date Type Operation

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Journal Article

visible-photocatalytic hydrogen evolution and simultaneous organic pollutant degradation over an urchin-like

Journal Article

Orlistat induces ferroptosis-like cell death of lung cancer cells

Journal Article

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article

Cystine oligomers successfully attached to peptide cysteine-rich fibrils

Christian Bortolini,Mingdong Dong

Journal Article

Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease

Min Fei, Li Xiang, Xichen Chai, Jingchun Jin, Tao You, Yiming Zhao, Changgeng Ruan, Yiwen Hao, Li Zhu

Journal Article

Graphene-like -BN supported polyhedral NiS/NiS nanocrystals with excellent photocatalytic performance

Journal Article

The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Journal Article

Mercury removal from aqueous solution using petal-like MoS2

Ragini Pirarath, Palani Shivashanmugam, Asad Syed, Abdallah M. Elgorban, Sambandam Anandan, Muthupandian Ashokkumar

Journal Article

Bamboo-like -doped carbon nanotubes encapsulating M(Co, Fe)-Ni alloy for electrochemical production of

Journal Article

Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine

Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG

Journal Article

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Journal Article

Effects of oxidizing environment on digestate humification and identification of substances governing the dissolved organic matter (DOM) transformation process

Journal Article

Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Journal Article